Treatments & Prevention
BRACE is a research charity dedicated solely to funding research into different forms of dementia.Â
Below you can find BRACE-funded research projects that have looked into finding new methods of prevention and treatments for dementia.
Please note that not all BRACE-funded research projects are featured on our website.
New targets for dementia treatment: Targeting the BCATc/ULK1/Vps34 axis in Alzheimer’s disease.
Aiming to test newly developed Huntington’s disease treatment on mice and human cells.Â
Modulation of the lysosomal cation channel TRPML1 as a novel therapeutic approach for Alzheimer's disease.Â
How a receptor in the brain called P2X7R influences Lewy body formation, and which types of brain cell are responsible. Â
Characterising T-cell responses in dementia: a protective role for gut-brain peptides. Exploring the role of the "hunger hormone".
Investigating the interaction of APOE4 with TDP43 proteinopathy in driving neurodegeneration.
Research from 2010 - 2022:
This research will increase the understanding of α-synuclein clumping and accelerate the finding of a cure.
This study may pave the way for an NHS funded trial into the effects of oral hygiene and the progression of Alzheimer’s.
Does lowering futile autophagosome synthesis alleviate aggregation-prone protein toxicity in dementia?
This research will examine the effects of ghrelin on human brain cells treated with toxic amyloid-β.
Protein interactions and mitochondrial dynamics in dementia with Lewy bodies - A PhD studentship and pilot study.